Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

What happens to cells on engrafting into the brain in animal models to treat Parkinson’s disease is unclear. Here, the authors use scRNA-seq to examine ventral midbrain (VM)-patterned human embryonic stem cells after functional maturation in a pre-clinical rat model for Parkinson’s disease and ident...

Descripción completa

Detalles Bibliográficos

Autores principales:	Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K. Björklund, Yogita Sharma, Andreas Heuer, Linda Gillberg, Deirdre B. Hoban, Tiago Cardoso, Andrew F. Adler, Marcella Birtele, Hilda Lundén-Miguel, Nikolaos Volakakis, Agnete Kirkeby, Thomas Perlmann, Malin Parmar
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2020-05-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-020-16225-5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!