Personalized and muscle-specific OXPHOS measurement with integrated CrCEST MRI and proton MR spectroscopy

Abstract Creatine chemical exchange saturation transfer (CrCEST) MRI is an emerging high resolution and noninvasive method for measuring muscle specific oxidative phosphorylation (OXPHOS). However, CrCEST measurements are sensitive to changes in muscle pH, which might confound the measurement and in...

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Hlavní autoři:	Ryan R. Armbruster, Dushyant Kumar, Blake Benyard, Paul Jacobs, Aditi Khandavilli, Fang Liu, Ravi Prakash Reddy Nanga, Shana McCormack, Anne R. Cappola, Neil Wilson, Ravinder Reddy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-06-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-49253-6
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