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Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver

Abstract Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is widely prescribed to treat hyperlipidemia and has therapeutic potential in liver and kidney diseases. However, fenofibrate is also associated with adverse effects, including elevated creatinine and liver and kid...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Venkat R. Pannala, Michele R. Balik-Meisner, Deepak Mav, Dhiral P. Phadke, Elizabeth H. Scholl, Ruchir R. Shah, Warren Casey, Scott S. Auerbach, Anders Wallqvist
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2025-10-01
Sraith:Scientific Reports
Ábhair:
Rochtain ar líne:https://doi.org/10.1038/s41598-025-20731-1
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