The CD8+ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIXTM Adjuvant

We recently described the induction of an efficient CD8+ T cell-mediated immune response against a tumor-associated antigen (TAA) uploaded in engineered exosomes used as an immunogen delivery tool. This immune response cleared tumor cells inoculated after immunization, and controlled the growth of t...

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Hlavní autoři:	Francesco Manfredi, Paola di Bonito, Barbara Ridolfi, Simona Anticoli, Claudia Arenaccio, Chiara Chiozzini, Adriana Baz Morelli, Maurizio Federico
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2016-11-01
Edice:	Vaccines
Témata:	adjuvant exosomes Nef HPV-E6 CD8+ T immune response
On-line přístup:	http://www.mdpi.com/2076-393X/4/4/42
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