Assessing the Influence of Urine pH on the Efficacy of Ciprofloxacin and Fosfomycin in Immunocompetent and Immunocompromised Murine Models of <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Infection in the Lower Urinary Tract

In vitro studies have suggested that acidic pH may reduce and increase the efficacy of ciprofloxacin and fosfomycin, respectively, when used to treat <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> infections. We assessed the effects of acidic, neutral, and alkaline urine pH on the efficacy...

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Autori principali:	Soraya Herrera-Espejo, Marta Carretero-Ledesma, Manuel Anselmo Bahamonde-García, Elisa Cordero, Jerónimo Pachón, María Eugenia Pachón-Ibáñez
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-09-01
Serie:	Antibiotics
Soggetti:	<i>Escherichia coli</i> <i>Klebsiella pneumoniae</i> urinary tract infection urine pH ciprofloxacin fosfomycin
Accesso online:	https://www.mdpi.com/2079-6382/13/9/827
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