SAGA–CORE subunit Spt7 is required for correct Ubp8 localization, chromatin association and deubiquitinase activity

Abstract Background Histone H2B deubiquitination is performed by numerous deubiquitinases in eukaryotic cells including Ubp8, the catalytic subunit of the tetrameric deubiquitination module (DUBm: Ubp8; Sus1; Sgf11; Sgf73) of the Spt-Ada-Gcn5 acetyltransferase (SAGA). Ubp8 is linked to the rest of S...

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Үндсэн зохиолчид:	Carme Nuño-Cabanes, Varinia García-Molinero, Manuel Martín-Expósito, María-Eugenia Gas, Paula Oliete-Calvo, Encar García-Oliver, María de la Iglesia-Vayá, Susana Rodríguez-Navarro
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2020-10-01
Цуврал:	Epigenetics & Chromatin
Нөхцлүүд:	SAGA Histone deubiquitination Spt7 Transcription Yeast
Онлайн хандалт:	http://link.springer.com/article/10.1186/s13072-020-00367-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!