C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin β1 glycosylation and activity.

Cancer cell invasion and metastasis are the primary causes of treatment failure and death in hepatocellular carcinoma (HCC). We previously reported that core 1 β1,3-galactosyltransferase (C1GALT1) is frequently overexpressed in HCC tumors and its expression is associated with advanced tumor stage, m...

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Auteurs principaux:	Chiung-Hui Liu, Rey-Heng Hu, Miao-Juei Huang, I-Rue Lai, Chia-Hua Chen, Hong-Shiee Lai, Yao-Ming Wu, Min-Chuan Huang
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2014-01-01
Collection:	PLoS ONE
Accès en ligne:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094995&type=printable
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