QR kód

Characterization of DNA damage repair pathway utilization in high-grade serous ovarian cancers yields rational therapeutic approaches

While poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have improved the prognosis of ovarian high-grade serous carcinoma (HGSC) tumors that are homologous recombination (HR) deficient (HRD), new therapeutic strategies are needed for tumors that are HR proficient (HRP) because they demonstrate...

Celý popis

Uloženo v:
Hlavní autoři: Erika Nakatsuka, Lijun Tan, Brianna Cunneen, Caroline Foster, Yu Leo Lei, Karen McLean
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-12-01
Edice:Translational Oncology
Témata:
DNA damage repair
Homologous recombination
Non-homologous end-joining
ATM
PARP
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1936523324002468
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky