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Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages

Background: Tissue-resident macrophages have mixed developmental origins. They derive in variable extent from yolk sac (YS) hematopoiesis during embryonic development. Bone marrow (BM) hematopoietic progenitors give rise to tissue macrophages in postnatal life, and their contribution increases upon...

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Main Authors: Sara Elhag, Christopher Stremmel, Annette Zehrer, Josefine Plocke, Roman Hennel, Michaela Keuper, Clarissa Knabe, Julia Winterhalter, Vanessa Gölling, Lukas Tomas, Tobias Weinberger, Maximilian Fischer, Lulu Liu, Franziska Wagner, Michael Lorenz, Konstantin Stark, Hans Häcker, Marc Schmidt-Supprian, Uwe Völker, Martin Jastroch, Kirsten Lauber, Tobias Straub, Barbara Walzog, Elke Hammer, Christian Schulz
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
macrophages
yolk sac
inflammasome
Online Access:https://www.mdpi.com/2073-4409/10/12/3564
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