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Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing

Neuroendocrine tumors (NETs) occur primarily in the small intestine, lung, and pancreas. Due to their rarity compared to other malignancies in these organs, their complex biology remains poorly understood, including their oncogenesis, tumor composition, and the intriguing phenomena of mixed neuroend...

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Principais autores: Einav Somech, Debdatta Halder, Avishay Spitzer, Chaya Barbolin, Michael Tyler, Reut Halperin, Moshe Biton, Amit Tirosh, Itay Tirosh
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2025-07-01
Serier:eLife
Fag:
neuroendocrine tumors
small intestine
single-cell RNA-seq
cell cycle
tumor heterogeneity
Online adgang:https://elifesciences.org/articles/101153
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