Safety and efficacy of once-daily dexfadrostat phosphate in patients with primary aldosteronism: a randomised, parallel group, multicentre, phase 2 trialResearch in context

Summary: Background: Primary aldosteronism (PA) is caused by autonomous aldosterone overproduction and characterised by uncontrolled hypertension. There are currently no treatments that target aldosterone synthesis. We evaluated the safety and efficacy of a novel aldosterone synthase inhibitor, dex...

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Detalhes bibliográficos

Principais autores:	Paolo Mulatero, Gregoire Wuerzner, Michael Groessl, Elisa Sconfienza, Aikaterini Damianaki, Vittorio Forestiero, Bruno Vogt, Hans Brunner, Teresa Gerlock, Ronald Steele, Christoph Schumacher
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-05-01
Colecção:	EClinicalMedicine
Assuntos:	Aldosterone Renin Aldosterone synthase inhibition Primary aldosteronism Hypertension
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S258953702400155X
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