Folic acid-modified ginger-derived extracellular vesicles for targeted treatment of rheumatoid arthritis by remodeling immune microenvironment via the PI3K-AKT pathway

Abstract Rheumatoid arthritis (RA), a form of autoimmune inflammation, is marked by enduring synovial inflammation and the subsequent impairment of joint function. Despite the availability of conventional treatments, they are often marred by significant side effects and the associated high costs. Pl...

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Asıl Yazarlar:	Ruina Han, Dongyang Zhou, Ning Ji, Zhifeng Yin, Jian Wang, Qin Zhang, Hao Zhang, Jinlong Liu, Xinru Liu, Han Liu, Qinglin Han, Jiacan Su
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	BMC 2025-01-01
Seri Bilgileri:	Journal of Nanobiotechnology
Konular:	Rheumatoid arthritis Plant-derived extracellular vesicles Folate receptor targeting Immune microenvironment PI3K-AKT pathway
Online Erişim:	https://doi.org/10.1186/s12951-025-03096-5
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