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Transcriptomic Analyses Reveal Differential Gene Expression of Immune and Cell Death Pathways in the Brains of Mice Infected with West Nile Virus and Chikungunya Virus

West Nile virus (WNV) and chikungunya virus (CHIKV) are arboviruses that are constantly (re-)emerging and expanding their territory. Both viruses often cause a mild form of disease, but severe forms of the disease can consist of neurological symptoms, most often observed in the elderly and young chi...

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Hlavní autoři: Stephanie M. Lim, Henk-Jan van den Ham, Minoushka Oduber, Eurydice Martina, Fatiha Zaaraoui-Boutahar, Jeroen M. Roose, Wilfred F. J. van IJcken, Albert D. M. E. Osterhaus, Arno C. Andeweg, Penelope Koraka, Byron E. E. Martina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017-08-01
Edice:Frontiers in Microbiology
Témata:
transcriptomics
Genomics
West Nile virus
chikungunya virus
neuroinvasive disease
cell death mechanisms
On-line přístup:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01556/full
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