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Metabolotheranostics of pancreatic cancer by targeting choline, glutamine, and glucose transporters with photoimmunotherapy

Abstract Altered choline, glutamine, and glucose metabolism form a triumvirate of metabolic reprogramming in most cancers that significantly influences growth, progression, and response to treatment. Photoimmunotherapy (PIT) is a highly target-specific treatment where a targeting antibody (Ab) is co...

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Principais autores: Puneet Khandelwal, Jiefu Jin, James D. Barnett, Yelena Mironchik, Balaji Krishnamachary, Saleem Yousf, Raj Kumar Sharma, Hisataka Kobayashi, Zaver M. Bhujwalla
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-05-01
Series:npj Imaging
Acceso en liña:https://doi.org/10.1038/s44303-026-00175-6
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