Semaglutide Modulates Proinflammatory Epicardial Adipogenesis With Paracrine Effects on hiPSC-Atrial Cardiomyocytes

Summary: Inflamed epicardial fat (EAT) accumulation around the myocardium and coronaries is a risk factor for cardiovascular disease. Glucagon-like peptide receptor-agonists 1 improves the insulin response and reduces EAT thickness. We aimed to demonstrate the effect of semaglutide on proinflammator...

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Detalhes bibliográficos

Principais autores:	Rumeysa Basdas, MSc, José Manuel Martínez-Cereijo, MD, PhD, Ángel L. Fernández, MD, PhD, Laura Reija, MD, Alba Cabaleiro, MSc, Susana Belén Bravo, PhD, José R. González-Juanatey, MD, PhD, Sonia Eiras, PhD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	JACC: Basic to Translational Science
Assuntos:	adipogenesis epicardial fat metabolism semaglutide
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452302X25001615
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