The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma

Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its clinical application and efficacy is severely restricted by its drug resistance properties. O6-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme, which can repair the DNA damage caused by TMZ. A large...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Haoyue Xu, Yongkang Zhang, Linfeng Li, Yanhong Ren, Feng Qian, Lansheng Wang, Hongwei Ma, Ankang Quan, Hongmei Liu, Rutong Yu
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Taylor & Francis Group 2023-12-01
श्रृंखला:	Drug Delivery
विषय:	Glioma drug-resistance siMGMT P(TMZ)n
ऑनलाइन पहुंच:	https://www.tandfonline.com/doi/10.1080/10717544.2022.2152911
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