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SPIRIT 2025 statement: Updated guideline for protocols of randomised trials.

<h4>Importance</h4>The protocol of a randomised trial is the foundation for study planning, conduct, reporting, and external review. However, trial protocols vary in their completeness and often do not address key elements of design and conduct. The SPIRIT (Standard Protocol Items: Recommendations f...

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Principais autores: An-Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F Schulz, Gary S Collins, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana R Elbourne, Andrew J Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, John P A Ioannidis, Brennan C Kahan, Rachel L Knowles, Sarah E Lamb, Steff Lewis, Elizabeth Loder, Martin Offringa, Philippe Ravaud, Dawn P Richards, Frank W Rockhold, David L Schriger, Nandi L Siegfried, Sophie Staniszewska, Rod S Taylor, Lehana Thabane, David J Torgerson, Sunita Vohra, Ian R White, Asbjørn Hróbjartsson
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2025-04-01
coleção:PLoS Medicine
Acesso em linha:https://doi.org/10.1371/journal.pmed.1004589
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