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Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces

Tightly controlled recruitment of telomerase, a low-abundance enzyme, to telomeres is essential for regulated telomere synthesis. Recent studies in human cells revealed that a patch of amino acids in the shelterin component TPP1, called the TEL-patch, is essential for recruiting telomerase to telome...

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Autors principals: Xichan Hu, Jinqiang Liu, Hyun-IK Jun, Jin-Kwang Kim, Feng Qiao
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2016-06-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/15470
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