In Situ Microscopy with Real-Time Image Analysis Enables Online Monitoring of Technical Protein Crystallization Kinetics in Stirred Crystallizers

Controlling protein crystallization processes is essential for improving downstream processing in biotechnology. This study investigates the combination of machine learning-based image analysis and in situ microscopy for real-time monitoring of protein crystallization kinetics. The experimental rese...

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Autori principali:	Julian Mentges, Daniel Bischoff, Brigitte Walla, Dirk Weuster-Botz
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-11-01
Serie:	Crystals
Soggetti:	technical protein crystallization crystal image analysis downstream processing protein aggregate formation crystal growth kinetics
Accesso online:	https://www.mdpi.com/2073-4352/14/12/1009
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