Serendipitous Identification of Azine Anticancer Agents Using a Privileged Scaffold Morphing Strategy

The use of privileged scaffolds as a starting point for the construction of libraries of bioactive compounds is a widely used strategy in drug discovery and development. Scaffold decoration, morphing and hopping are additional techniques that enable the modification of the chosen privileged framewor...

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Detalhes bibliográficos

Principais autores:	Silvia Cesarini, Ilaria Vicenti, Federica Poggialini, Silvia Filippi, Eleonora Mancin, Lia Fiaschi, Elisa De Marchi, Federica Giammarino, Chiara Vagaggini, Bruno Mattia Bizzarri, Raffaele Saladino, Elena Dreassi, Maurizio Zazzi, Lorenzo Botta
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-03-01
coleção:	Molecules
Assuntos:	privileged scaffold triazines pyrimidines pyridines scaffold morphing anticancer activity
Acesso em linha:	https://www.mdpi.com/1420-3049/29/7/1452
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