Mechanisms of PTEN-regulated PDK1 in modulating malignant phenotypes of clear cell renal cell carcinoma
Background and purpose: The aberrant activation of pyruvate dehydrogenase kinase 1 (PDK1) drives tumor microenvironment remodeling and metastasis through mediating the Warburg effect. As a critical tumor-suppressive phosphatase, phosphatase and tensin homolog deleted on chromoseme ten (PTEN) activat...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Editorial Office of China Oncology
2025-08-01
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| Col·lecció: | Zhongguo aizheng zazhi |
| Matèries: | |
| Accés en línia: | http://www.china-oncology.com/thesisDetails#10.19401/j.cnki.1007-3639.2025.08.004 |
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