The Role of Non-Human Sialic Acid Neu5Gc-Containing Glycoconjugates in Human Tumors: A Review of Clinical and Experimental Evidence
N-Glycolylneuraminic acid (Neu5Gc) is a sialic acid variant commonly found in most mammals but not synthesized by humans due to an inactivating mutation in the CMP-Neu5Ac hydroxylase (<i>CMAH</i>) gene. Despite this, Neu5Gc-containing molecules are consistently detected in human tissues, particularl...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2025-02-01
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| Schriftenreihe: | Biomolecules |
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| Online-Zugang: | https://www.mdpi.com/2218-273X/15/2/253 |
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