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Drug repurposing in Rett and Rett-like syndromes: a promising yet underrated opportunity?

Rett syndrome (RTT) and Rett-like syndromes [i.e., CDKL5 deficiency disorder (CDD) and FOXG1-syndrome] represent rare yet profoundly impactful neurodevelopmental disorders (NDDs). The severity and complexity of symptoms associated with these disorders, including cognitive impairment, motor dysfuncti...

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Tallennettuna:
Päätekijät: Claudia Fuchs, Peter A. C. ‘t Hoen, Annelieke R. Müller, Friederike Ehrhart, Clara D. M. Van Karnebeek
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2024-07-01
Sarja:Frontiers in Medicine
Aiheet:
Rett syndrome
CDKL5 deficiency disorder
FOXG1-syndrome
shared molecular pathways
common drug targets
drug repurposing
Linkit:https://www.frontiersin.org/articles/10.3389/fmed.2024.1425038/full
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