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Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC50 = 5...

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Bibliografiset tiedot
Päätekijät: Kong Mun Lo, Aurangzeb Hasan, Seema Zareen, Wan Yong Ho, Swee Keong Yeap, Muhammad Nadeem Akhtar, Noorjahan Banu Alitheen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2013-08-01
Sarja:Molecules
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Linkit:http://www.mdpi.com/1420-3049/18/8/10042
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