An mRNA Vaccine Expressing Blood-Stage Malaria Antigens Induces Complete Protection Against Lethal <i>Plasmodium yoelii</i>
Background and Objectives: To evaluate the mRNA vaccine platform for blood-stage <i>Plasmodium</i> parasites, we completed a proof-of-concept study using the <i>P. yoelii</i> mouse model of malaria and two mRNA-based vaccines. Both encoded <i>Py</i>MSP1<sub>19</sub> fused to <i>Py</i>MSP8 (<i>Py</i>...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2025-06-01
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| Serie: | Vaccines |
| Soggetti: | |
| Accesso online: | https://www.mdpi.com/2076-393X/13/7/702 |
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