Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation

Nicotinic acetylcholine receptors (nAChRs) have been historically defined as ligand-gated ion channels and function as such in the central and peripheral nervous systems. Recently, however, non-ionic signaling mechanisms via nAChRs have been demonstrated in immune cells. Furthermore, the signaling p...

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Hlavní autoři:	Arik J. Hone, J. Michael McIntosh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-04-01
Edice:	Pharmacological Research
Témata:	Nicotinic acetylcholine receptor subunits α7, α9, and α10 Neuropathic pain Chronic pain Inflammatory pain Chemotherapy-induced neuropathic pain α-conotoxin RgIA
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1043661823000713
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