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The Effect of a Cyclooxygenase 2 Inhibitor on Early Degenerated Human Nucleus Pulposus Explants

Study Design Preclinical in vitro culture of human degenerated nucleus pulposus (NP) tissue. Objective Cyclooxygenase 2 inhibitors (e.g., celecoxib) inhibit prostaglandin E 2 (PGE 2 ) production, and they have been shown to upregulate regeneration of articular cartilage. In this study, we developed...

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Bibliografiske detaljer
Principais autores: Bart van Dijk, Esther Potier, Ruud Licht, Laura Creemers, Keita Ito MD, ScD
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2014-02-01
Serier:Global Spine Journal
Online adgang:https://doi.org/10.1055/s-0033-1359724
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