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A divide-and-conquer strategy in tumor sampling enhances detection of intratumor heterogeneity in routine pathology: A modeling approach in clear cell renal cell carcinoma [version 1; referees: 2 approved]

Intratumor heterogeneity (ITH) is an inherent process in cancer development which follows for most of the cases a branched pattern of evolution, with different cell clones evolving independently in space and time across different areas of the same tumor. The determination of ITH (in both spatial and...

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Hlavní autoři: José I. Lopez, Jesús M. Cortes
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000 Research Ltd 2016-03-01
Edice:F1000Research
Témata:
On-line přístup:http://f1000research.com/articles/5-385/v1
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