FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy

ABSTRACT FAM46C is a multiple myeloma (MM) tumor suppressor whose function is only starting to be elucidated. We recently showed that in MM cells FAM46C triggers apoptosis by inhibiting autophagy and altering intracellular trafficking and protein secretion. To date, both a physiological characteriza...

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Detalles Bibliográficos

Principais autores:	Marilena Mancino, Giancarlo Lai, Federica De Grossi, Alessandro Cuomo, Lara Manganaro, Giacomo M. Butta, Ivan Ferrari, Elisa Vicenzi, Guido Poli, Elisa Pesce, Stefania Oliveto, Stefano Biffo, Nicola Manfrini
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2023-08-01
Series:	Microbiology Spectrum
Assuntos:	FAM46C TENT5C HIV-1 autophagy interferons lentiviruses
Acceso en liña:	https://journals.asm.org/doi/10.1128/spectrum.05211-22
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