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miR-186 regulates epithelial–mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1

Objectives: Nasopharyngeal carcinoma (NPC) is an aggressive epithelial cancer. The expression of miR-186 is decreased in a variety of malignancies and can promote the invasion and metastasis of cancer cells. This study aimed to explore the role and possible mechanism of miR-186 in the metastasis and...

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Principais autores: Liangke Tang, Yalang Xiang, Jing Zhou, Tao Li, Tingting Jia, Guobo Du
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-01-01
Serier:Brazilian Journal of Otorhinolaryngology
Fag:
miR-186
ZEB1
Nasopharyngeal carcinoma
Epithelial–mesenchymal transformation
Metastasis
Online adgang:http://www.sciencedirect.com/science/article/pii/S180886942300126X
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