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Hematopoietic stem cells in co-culture with mesenchymal stromal cells - modeling the niche compartments in vitro

Background Hematopoietic stem cells located in the bone marrow interact with a specific microenvironment referred to as the stem cell niche. Data derived from ex vivo co-culture systems using mesenchymal stromal cells as a feeder cell layer suggest that cell-to-cell contact has a significant impact...

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Hlavní autoři: Duohui Jing, Ana-Violeta Fonseca, Nael Alakel, Fernando A. Fierro, Katrin Muller, Martin Bornhauser, Gerhard Ehninger, Denis Corbeil, Rainer Ordemann
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2010-04-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/5549
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