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SOCS5, targeted by miR-155-5p, plays a negative regulatory role in pulmonary hypertension through inhibiting JAK2/STAT3 signaling pathway

Abstract Pulmonary hypertension (PH) is a chronic pulmonary vascular disease and causes massive deaths. Here, we intended to investigate the function and mechanism of SOCS5 in PH. We engineered a hypoxia-induced PH model in mice. HE staining were implemented to evaluate pathological alterations in t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lili Sun, Lihua Liu, Dongxue Liang, Linlin Liu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2024-01-01
Cyfres:BMC Pulmonary Medicine
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s12890-024-02857-6
Tagiau: Ychwanegu Tag
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