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Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and a mass spectrometry workflow to analyze tissue...

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Detalles Bibliográficos
Principais autores: Paul D. Piehowski, Ying Zhu, Lisa M. Bramer, Kelly G. Stratton, Rui Zhao, Daniel J. Orton, Ronald J. Moore, Jia Yuan, Hugh D. Mitchell, Yuqian Gao, Bobbie-Jo M. Webb-Robertson, Sudhansu K. Dey, Ryan T. Kelly, Kristin E. Burnum-Johnson
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2020-01-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-019-13858-z
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