Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa

Abstract Background In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in infectious diseases has thus remained unclear. Methods We analyzed 3204 patients...

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Detalhes bibliográficos

Principais autores:	Kazuo Kawasugi, Hideo Wada, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba, Kohji Okamoto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-02-01
coleção:	Thrombosis Journal
Assuntos:	Disseminated intravascular coagulation Hypofibrinogenemia Thrombomodulin Post-marketing surveillance Infectious disease Mortality
Acesso em linha:	https://doi.org/10.1186/s12959-021-00264-z
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