Complex segregation analysis of pedigrees from the Gilda Radner Familial Ovarian Cancer Registry reveals evidence for mendelian dominant inheritance.

BACKGROUND:Familial component is estimated to account for about 10% of ovarian cancer. However, the mode of inheritance of ovarian cancer remains poorly understood. The goal of this study was to investigate the inheritance model that best fits the observed transmission pattern of ovarian cancer amon...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Bamidele O Tayo, Richard A DiCioccio, Yulan Liang, Maurizio Trevisan, Richard S Cooper, Shashikant Lele, Lara Sucheston, Steven M Piver, Kunle Odunsi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2009-06-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC2694280?pdf=render
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