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Full Regio- and Stereoselective Protocol for the Synthesis of New Nicotinoids via Cycloaddition Processes with the Participation of Trans-Substituted Nitroethenes: Comprehensive Experimental and MEDT Study

[3 + 2] Cycloaddition reactions with the participation of <i>Z</i>-C-(3-pyridyl)-<i>N</i>-methylnitrone and series of <i>E</i>-2-R-nitroethenes were both experimentally and theoretically explored in the framework of Molecular Electron Density Theory. It was found that all considered processes are re...

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Main Authors: Jowita Kras, Przemysław Woliński, Roman Nagatsky, Oleg M. Demchuk, Radomir Jasiński
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
[3 + 2] cycloaddition
nitrones
nitroalkenes
nicotinoids
molecular electron density theory
Online Access:https://www.mdpi.com/1420-3049/28/8/3535
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