In vitro modeling of amyotrophic lateral sclerosis with induced pluripotent stem cell technology-derived cell line ORIONi002-A

We present here a new iPS cell line for modeling sporadic form of ALS. Cell line was generated by reprogramming skin fibroblasts isolated with explant culture technology from skin biopsy, donated by ALS patient. For reprogramming, polycistronic self-replicating RNA vector was used and derived iPS ce...

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Autores principales:	Jan Strnadel, Hugo M. Dumortier, Dominika Hajduchova, Romana Zahumenska, Vladimir Nosal, Marek Smolar, Juraj Marcinek, Michal Kalman, Sandra Mersakova, Dusan Brany, Stefan Juhas, Jana Juhasova, Hana Studenovska, Barbora Mitruskova, Stanislava Suroviakova, Slavomira Novakova, Henrieta Skovierova, Egon Kurca, Renata Pecova, Lukas Plank, Erika Halasova
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2022-08-01
Colección:	Stem Cell Research
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1873506122002197
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