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Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones

A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal development, a substantial proportion of Lasso is released i...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Nickolai V Vysokov, John-Paul Silva, Vera G Lelianova, Jason Suckling, John Cassidy, Jennifer K Blackburn, Natalia Yankova, Mustafa BA Djamgoz, Serguei V Kozlov, Alexander G Tonevitsky, Yuri A Ushkaryov
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2018-11-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/37935
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