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A Review of the Inhibition of the Mitochondrial ATP Synthase by IF1 in vivo: Reprogramming Energy Metabolism and Inducing Mitohormesis

The ATPase Inhibitory Factor 1 (IF1) is the physiological inhibitor of the mitochondrial ATP synthase. Herein, we summarize the regulation of the expression and activity of IF1 as a main driver of the activity of oxidative phosphorylation (OXPHOS) in mammalian tissues. We emphasize that the expressi...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ana García-Aguilar, José M. Cuezva
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2018-09-01
Rangatū:Frontiers in Physiology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fphys.2018.01322/full
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