Early Plasma Nuclear DNA, Mitochondrial DNA, and Nucleosome Concentrations Are Associated With Acute Kidney Injury in Critically Ill Trauma Patients

OBJECTIVES:. Circulating nucleic acids, alone and in complex with histones as nucleosomes, have been proposed to link systemic inflammation and coagulation after trauma to acute kidney injury (AKI). We sought to determine the association of circulating nucleic acids measured at multiple time points...

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Hauptverfasser:	Hilary E. Faust, MD, MTR, Oluwatosin Oniyide, BS, Yiyue Wang, BS, Caitlin M. Forker, BA, Thomas Dunn, BS, Wei Yang, PhD, Paul N. Lanken, MD, Carrie A. Sims, MD, PhD, Nadir Yehya, MD, MSCE, Jason D. Christie, MD, Nuala J. Meyer, MD, MTR, John P. Reilly, MD, MSCE, Nilam S. Mangalmurti, MD, Michael G. S. Shashaty, MD, MSCE
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wolters Kluwer 2022-04-01
Schriftenreihe:	Critical Care Explorations
Online-Zugang:	http://journals.lww.com/10.1097/CCE.0000000000000663
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Early Plasma Nuclear DNA, Mitochondrial DNA, and Nucleosome Concentrations Are Associated With Acute Kidney Injury in Critically Ill Trauma Patients

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