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Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms

The Arp2/3 complex regulates many cellular processes by stimulating formation of branched actin filament networks. Because three of its seven subunits exist as two different isoforms, mammals produce a family of Arp2/3 complexes with different properties that may be suited to different physiological...

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Detalhes bibliográficos
Principais autores: Ottilie von Loeffelholz, Andrew Purkiss, Luyan Cao, Svend Kjaer, Naoko Kogata, Guillaume Romet-Lemonne, Michael Way, Carolyn A. Moores
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2020-07-01
coleção:Biology Open
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Acesso em linha:http://bio.biologists.org/content/9/7/bio054304
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