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Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

In the current study, eight new hybrids of the NSAIDs, ibuprofen and ketoprofen with five pyrrolizine/indolizine derivatives were designed and synthesized. The chemical structures of these hybrids were confirmed by spectral and elemental analyses. The antiproliferative activities of these hybrids (5...

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Hlavní autoři: Mohammed A. S. Abourehab, Alaa M. Alqahtani, Faisal A. Almalki, Dana M. Zaher, Ashraf N. Abdalla, Ahmed M. Gouda, Eman A. M. Beshr
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-10-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/26/21/6582
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