Xin-Fu-Kang oral liquid improves cardiac function and attenuates miR-223–associated NF-κB/NLRP3 pyroptotic signaling in chronic heart failure

BackgroundPyroptotic signaling involving nuclear factor-kappa B (NF-κB) and NOD-like receptor family pyrin domain–containing 3 (NLRP3) has been implicated in chronic heart failure (CHF). Xin-Fu-Kang (XFK) is a nine-herb formula used clinically for CHF with “qi deficiency and blood stasis.” Although...

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Autors principals:	Zelin Ye, Mingrui Liu, Xiaohan Zhang, Huaqin Wu, Zhiling Qiu, Ruoning Chai, Yuanhui Hu
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-12-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	Xin-Fu-Kang chronic heart failure pyroptosis miR-223 NF-κB NLRP3
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1697422/full
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