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Diminazene aceturate mitigates cardiomyopathy by interfering with renin-angiotensin system in a septic rat model

Abstract Background There were limited studies investigating treatments of septic cardiomyopathy (SCM), which is a common complication during sepsis. A septic rat model created by cecal ligation and puncture (CLP) was used to investigate the effects of diminazene aceturate (DIZE) in SCM. Methods A t...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Zhaoqing Lu, Di Wu, Zheng Wang, Hanyu Zhang, Yufan Du, Guoxing Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-07-01
Schriftenreihe:BMC Pharmacology and Toxicology
Schlagworte:
Septic cardiomyopathy
Diminazene aceturate
Angiotensin-converting enzyme
Renin-angiotensin system
Online-Zugang:https://doi.org/10.1186/s40360-022-00584-4
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