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Encephalopathy induced by Alzheimer brain inoculation in a non-human primate

Abstract Alzheimer’s disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of misfolded and aggregated β-amyloid peptides (Aβ) and tau proteins. Iatrogenic induction of Aβ is suspected in patients exposed to pituitary-...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E. Koch, Fanny Petit, Pauline Gipchtein, Stephen J. Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, French Neuropathology Network, Emmanuel Brouillet, Luc Buée, Emmanuel E. Comoy, Fabien Pifferi, Jean-Luc Picq, Marc Dhenain
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-09-01
Schriftenreihe:Acta Neuropathologica Communications
Schlagworte:
Alzheimer’s disease
β-Amyloid pathology
Cerebral atrophy
Cognitive impairment
Microcebus murinus
Mouse
Online-Zugang:http://link.springer.com/article/10.1186/s40478-019-0771-x
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