Amyloid-Beta Peptides and Activated Astroglia Impairs Proliferation of Nerve Growth Factor Releasing Cells In Vitro: Implication for Encapsulated Cell Biodelivery-Mediated AD Therapy

Alzheimer’s disease (AD) treatment is constrained due to the inability of peripherally administered therapeutic molecules to cross the blood–brain barrier. Encapsulated cell biodelivery (ECB) devices, a tissue-targeted approach for local drug release, was previously optimized for human mature nerve...

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Auteurs principaux:	Sumonto Mitra, Silvia Turchetto, Winant Van Os, Lars U. Wahlberg, Bengt Linderoth, Homira Behbahani, Maria Eriksdotter
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-10-01
Collection:	Cells
Sujets:	Alzheimer’s disease (AD) astrocytes amyloid beta (Aβ) encapsulated cell biodelivery (ECB) nerve growth factor (NGF) drug delivery strategy optimization
Accès en ligne:	https://www.mdpi.com/2073-4409/10/11/2834
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