Characterization of POU2F3-expressing large cell neuroendocrine carcinoma of the lung: A comprehensive analysis of morphology, immunohistochemistry, and genomic alterations

Large cell neuroendocrine carcinoma (LCNEC) is a neuroendocrine carcinoma (NEC) of the lung that is characterized by its heterogeneous morphology, diverse immunophenotypes, and complex genomic profiles. Among LCNECs, a subset expressing the transcription factor POU2F3 (LCNEC-P) has been suggested to...

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Autori principali:	Ryota Matsuoka, Kei Asayama, Tomoki Nakagawa, Yoshihiko Murata, Ayako Suzuki, Yutaka Suzuki, Naohiro Kobayashi, Yukio Sato, Nobuyuki Hizawa, Hiroyoshi Tsubochi, Shunsuke Endo, Koichi Hagiwara, Toshiro Niki, Noriyoshi Fukushima, Kentaro Inamura, Daisuke Matsubara
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-01-01
Serie:	Cancer Treatment and Research Communications
Soggetti:	POU2F3 Small cell carcinoma Large cell neuroendocrine carcinoma Neuroendocrine carcinoma
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2468294226000225
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