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Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

How leukaemia cells invade the bone marrow by outcompeting haematopoietic cells is still unclear. Here, the authors used detailed cell number measurements in conjunction with a dual pulse labelling method to determine proliferation rates and followed the in vivo dynamics of AML disease progression.

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Autori principali: O. Akinduro, T. S. Weber, H. Ang, M. L. R. Haltalli, N. Ruivo, D. Duarte, N. M. Rashidi, E. D. Hawkins, K. R. Duffy, C. Lo Celso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2018-02-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-017-02376-5
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