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KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression

Hepatic lipid metabolism is controlled by integrated metabolic pathways. Excess accumulation of hepatic TG is a hallmark of nonalcoholic fatty liver disease, which is associated with obesity and insulin resistance. Here, we show that KH-type splicing regulatory protein (KSRP) ablation reduces hepati...

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Principais autores: Chu-Fang Chou, Xiaolin Zhu, Yi-Yu Lin, Karen L. Gamble, W. Timothy Garvey, Ching-Yi Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-02-01
coleção:Journal of Lipid Research
Assuntos:
circadian rhythms
fatty acid synthesis
KH-type splicing regulatory protein
liver
nuclear receptors/sterol-regulatory element binding protein 1• period 2
ribonucleic acid turnover
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520356091
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