A Reaction of <i>N</i>-Substituted Succinimides with Hydroxylamine as a Novel Approach to the Synthesis of Hydroxamic Acids

We describe a novel two-step approach for the synthesis of compounds with a hydroxyl-amide group (hydroxamic acids), which are widely known for their biological activity (histone deacetylase inhibitors, matrix metalloproteinases inhibitors and others). The first stage is the synthesis of <i>N</i>-su...

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Principais autores:	Bogdan A. Tretyakov, Svyatoslav Y. Gadomsky, Alexei A. Terentiev
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-04-01
Colecção:	Organics
Assuntos:	<i>N</i>-substituted succinimides hydroxylamine hydroxamic acids imide ring opening HDAC inhibitors MMP inhibitors
Acesso em linha:	https://www.mdpi.com/2673-401X/4/2/15
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